Splicing Busts a Move: Isoform Switching Regulates Migration
نویسندگان
چکیده
منابع مشابه
A Novel CDX2 Isoform Regulates Alternative Splicing
Gene expression is a dynamic and coordinated process coupling transcription with pre-mRNA processing. This regulation enables tissue-specific transcription factors to induce expression of specific transcripts that are subsequently amplified by alternative splicing allowing for increased proteome complexity and functional diversity. The intestine-specific transcription factor CDX2 regulates deve...
متن کاملCorrection: A Novel CDX2 Isoform Regulates Alternative Splicing
Citation: The PLOS ONE Staff (2014) Correction: A Novel CDX2 Isoform Regulates Alternative Splicing. PLoS ONE 9(10): e112164. doi:10.1371/journal.pone.0112164 Published October 23, 2014 Copyright: 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any m...
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Physiological changes during embryonic development are associated with changes in the isoform expression of both myocyte sarcomeric proteins and of erythrocyte haemoglobins. Cell type-specific isoform expression of these genes also occurs. Although these changes appear to be coordinated, it is unclear how changes in these disparate cell types may be linked. The transcription factor Hic2 is requ...
متن کاملTitle : Genome - wide characterization of isoform switching in Arabidopsis thaliana Running title : Isoform switching in
1 Department of Plant Systems Biology, VIB, Technologiepark 927, B-9052 Gent, Belgium (D.V., K.V.), Department of Plant Biotechnology and Bioinformatics, Ghent University, Technologiepark 927, B-9052 Gent, Belgium (D.V., K.V.) 2 Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, North Carolina Research Campus, Kannapolis, NC 28081, USA (A.R.E, Y.C.L., A.E.L) C...
متن کاملRbm20 regulates titin alternative splicing as a splicing repressor
Titin, a sarcomeric protein expressed primarily in striated muscles, is responsible for maintaining the structure and biomechanical properties of muscle cells. Cardiac titin undergoes developmental size reduction from 3.7 megadaltons in neonates to primarily 2.97 megadaltons in the adult. This size reduction results from gradually increased exon skipping between exons 50 and 219 of titin mRNA. ...
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ژورنال
عنوان ژورنال: Trends in Cell Biology
سال: 2020
ISSN: 0962-8924
DOI: 10.1016/j.tcb.2019.10.007